CHEST Journal. 1995;19 (2): 176-81. The 70 isolates were taken from diverse clinical specimens. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). {"url":"/signup-modal-props.json?lang=us\u0026email="}. (1968) Diseases of the chest. Seventy of Klebsiella pneumoniae isolates had been collected from some Hospitals in Baghdad city from October to December 2017. 1 - 5 Although single case reports discuss the clinical presentation of pneumonia caused by Escherichia coli or Actinobacillus spp., 6, 7 to the authors’ knowledge no large retrospective studies describe the … the Western countries, Klebsiella pneumoniae invasive syn-drome (KPIS) should be alerted when patients present atypi-cal vague symptoms including fever, chill, nausea, vomiting, and right upper quadrant tenderness. Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium.It appears as a mucoid lactose fermenter on MacConkey agar.. Lobar expansion (e.g. To retrospectively compare the computed tomographic (CT) features of liver abscesses caused by Klebsiella pneumoniae with those caused by other bacterial pathogens. Hansell DM. Klebsiella pneumonia usually results from aspiration of colonizing oropharyngeal microbes into the lower respiratory tract. 769-776. Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae: US Appearance and Aspiration Findings. by Wenlie Xie and Huixuan Jia. The presence of gram-negative rods in Gram-stained smears suggests Klebsiella; they maybe capsulated and non-sporing. Mosby Incorporated. Clin. 53 (4): 481-6. This occurs early and progresses quickly. Klebsiella pneumoniae(K. pneumoniae) is a Gram-negative, non-motile, capsulated, gas-producing enteric bacillus widely found in nature, and it belongs to the normal flora of the human oral cavity and intestine. Pulmonary infection can also be classified into several radiologic and pathologic patterns according to its morphologic features. Diagnosis: Klebsiella pneumonia (aka Friedländer’s pneumonia) - Images, diagnosis, treatment options, review - Thoracic Imaging Case. Massive necrosis (pulmonary gangrene) is a recognized complication. The past 3 decades have seen the emergence of an invasive liver abscess syndrome caused by Klebsiella pneumoniae that may manifest with metastatic infection to the eye, brain, or lung [1, 2]. There has been a considerable increase in the incidence of this type of pneumonia beginning in 1954 and reaching a peak in 1956, with 21 cases. Klebsiella pneumonia, also known as Friedländer pneumonia, refers to pneumonia resulting from an infection from the organism Klebsiella pneumoniae. Klebsiella pneumonia is a necrotizing process with a predilection for debilitated people. Also, lobar expansion is not specific for Klebsiella infection. Hoffman NR, Preston FS. Coronavirus: ... 2 Division of Diagnostic Radiology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. Case of the Week: August 27-September 3, 2009. After that, a 6-week course of amoxicillin-clavulanate (1 g every 12 h) was substituted. ADVERTISEMENT: Supporters see fewer/no ads. The Post-operative Abdomen - Surgicel … Sputum analysis grew Klebsiella pneumoniae. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). Klebsiella is also responsible for a significant number of community-acquired infections. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. ; Material is inoculated into blood agar and Mac Conkey agar medium and incubated aerobically. (2009) ISBN:0723434964. Acute Klebsiella pneumoniae pneumonia alone and with concurrent infection: comparison of clinical and thin-section CT findings. The three most common patterns are lobar pneumonia, bronchopneumonia, and interstitial pneumonia. It is not possible radiologically to pinpoint the causative organism. On CXR, consolidation is lobar and resembles streptococcus pneumonia. On CXR, consolidation is lobar and resembles streptococcus pneumonia. (2007) ISBN:B0011ZYZR2. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Klebsiella pneumonia | Radiology Reference Article | Radiopaedia.org. Check for errors and try again. This occurs early and progresses quickly. In comparison, cavitation is rare in pneumococcal pneumonia. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. 2. Necrotizing pneumonia can occur as a complication 6. Microbiol. Continuous improvement of the lesion was found on follow-up chest X-rays. Chronic Klebsiella pneumonia: a rare manifestation of Klebsiella pneumonia. Unable to process the form. K pneumoniae monomicrobial liver abscesses were associated with diabetes mellitus (P <.001), higher blood glucose levels at admission (P <.05), predominantly solid US appearances (P <.001), irregular or indistinct lesion margins (P <.05), less than 2 mL of pus aspirated (P <.001), and longer duration of antibiotic treatment (P <.05). Rev. Antibiotics sensitivity test was carried out toward 10 antibiotics using discs diffusion method. [12,17] Aspiration pneumonia should always be suspected if the infiltrates are present bilaterally in the dependent or posterior portions of the lungs. This organism can cause extensive pulmonary necrosis and frequent cavitation 1. Invasive community-acquired infections, including pyogenic liver abscesses, caused by hypervirulent Klebsiella pneumoniae (hvKp) strains have been well recognized worldwide. Klebsiella pneumoniae renal abscess Zhonghua Yi Xue Za Zhi (Taipei). K. pneumoniae is found in the normal flora of skin, mouth and intestines, where it does not cause disease. Friedlander's pneumonia. 2000 Oct;63(10):721-8. 3. Path. CT Appearance of Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae. 1. However, in general, the type of microorganism implicated in pneumonia can be identified (bacteria, viruses, or fungi). There can be variable features on chest HRCT which can also depend on current other organisms. Figure Klebsiella pneumoniae liver abscess cases (n=123) in an outpatient parenteral antibiotic therapy (OPAT) cohort in Singapore, 2006–11 (n=2229) View Large Image Figure Viewer; Download Hi-res image Download (PPT) Roughly 70% of patients with K pneumoniae abscesses were men. Klebsiella pneumoniae, a gram-negative organism, is an emerging common cause of PLA, particularly in patients with poorly controlled diabetes mellitus and without any pre-existing liver disease. Recommended Articles. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). WebMD does not provide medical advice, diagnosis or treatment. Extensive right upper lobe consolidation, with bulging of the horizontal fissure. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Imaging of Diseases of the Chest. Massive necrosis (pulmonary gangrene) is a recognized complication. Moon WK, Im JG, Yeon KM et-al. Introduction . Mosby Incorporated. Radiology 2007. Less common forms of infection include cellular bronchiolitis, septic embolism, miliary infection, and lung abscess. 2010;83 (994): 854-60. K. pneumoniae is also a well-known cause of community-acquired pneumonia. K. pneumoniaewas first discovered by Friedlander in 1882 and considered to be responsible for a severe form of lobar pneumonia. (2009) ISBN:0723434964. Klebsiella pneumoniae (K. pneumoniae) are bacteria that normally live in your intestines and feces. © 2005 - 2021 WebMD LLC. 27-05-2014 - Klebsiella pneumonia is refers to a pneumonia resulting from an infection from the organism Klebsiella pneumoniae. 2011;140 (4_MeetingAbstracts): . It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. Br J Radiol. 87: 319. 5. These bacteria are harmless when they’re in … Hansell DM. The disease is often overlooked in the Western physicians due to its rarity. Lippincott Williams &Wilkins. It has a high mortality rate of approximately 50% even with antimicrobial therapy. Imaging of Diseases of the Chest. Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis. {"url":"/signup-modal-props.json?lang=us\u0026email="}. Results: The mean age was 58.7 years and the male to female ratio was 10:14. The organism Klebsiella pneumoniae was first described by German microbiologist Carl Friedländer (1847-1887) in 1882, in a series of patients with Klebsiella pneumonia 7,8. Authors S ... diagnostic radiology studies, therapeutic modalities and risk factors associated with mortality were studied. Klebsiella pneumoniae- Pathogenicity and Clinical Manifestations. Since 1950, 76 proved cases of pneumonia due to Staphylococcus aureus have been seen at the Los Angeles County Hospital. Klebsiella pneumoniae is a Gram-negative bacteria and a well-known cause of community-acquired pneumonia, which accounts for less than 5% of all cases of pneumonia. Klebsiella species are a Gram-negative rod shaped bacteria belonging to the Enterobacteriaceae family. Gadkowski LB, Stout JE. Klebsiella spp. A report of 11 cases and appraisal of antibiotic therapy. 6. There tends to be a higher prevalence in older patients with alcoholism and debilitated hospitalized patients 3. See additional information. 61-year-old woman with a long-standing history of alcohol abuse presented with a sudden onset of cough, pleuritic chest pain, dyspnea, fever, and rigors. All rights reserved. Nineteen cases were seen in the first half of 1958. 8. In the setting of pneumonia, infection with K. pneumoniae is confirmed by either sputum culture analysis, blood culture analysis or midstream urine depending upon the illness. The spectrum includes. Chronic Klebsiella pneumonia was diagnosed and ceftazidime was changed to ceftriaxone 1 g every 12 h for 2 weeks. It is an important type of pneumonia because of its severity, high incidence of complications, and elevated mortality [1]. Often there can be extensive lobar opacification with air bronchograms. Check for errors and try again. There can b… VCU Department of Radiology VCU Medical Center. 4. Volume: 242 Issue: 3 pp. They are commonly found in the environment and in … A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases. This occurs early and progresses quickly. Klebsiella species cause a wide range of diseases including pneumonia, urinary tract infections (UTIs), bloodstream infections and sepsis. J Comput Assist Tomogr. In nosocomial pneumonia, patchy bronchial pneumonia is the most common finding and is likely caused by Gram-negative pathogens, especially Pseudomonas or Klebsiella. The Brant and Helms Solution. Klebsiella pneumoniae is a bacterium that normally lives inside human intestines, where it doesn't cause disease.. Massive necrosis (pulmonary gangrene) is a recognized complication. bulging of the horizontal fissure in this case) is less common nowadays with modern antibiotic treatment. Okada F, Ando Y, Honda K et-al. Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium that is found in the environment and has been associated with pneumonia in the alcoholic and diabetic patient population. These infections are particularly a problem among neonates, elderly and immunocompromised individuals. (1882) Virchow Arch. Friedlander, C. Über die Pseudomyceten bei der acuten fibrinösen Pneumoniae. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. E.Brant MW, A.Helms MC. 7. Complications of Klebsiella pneumonia: CT evaluation. Ono A. Cavitary pulmonary disease. Radiology 2011. All K. pneumoniae isolates were identified based on API 20 E and Vitek2 compact system. Anat. The hypervirulence of these novel community-acquired strains is mediated in part by their hypermucoviscous phenotypes associated with K1 and K2 capsule serotypes [ 3–5 ]. Often there can be extensive lobar opacification with air bronchograms. On CXR, consolidation is lobar and resembles streptococcus pneumonia. The bacterium typically colonizes human mucosal … Among these, sporadic hvKp-related community-acquired pneumonia (CAP) is an acute-onset, rapidly progressing disease that can likely turn fatal, if left untreated. … Conversely, various pathogens give rise to identical radiologic findings; e.g., bronchopneumonia can be caused by, for example, Staphylococcus aureus, Klebsiella, Proteus, or Pseudomonas. are commonly implicated as a cause of bacterial pneumonia in horses, but few reports describe the clinical presentation and progression of disease attributable to this organism. Klebsiella pneumoniae was first described by a German microbiologist and pathologist Carl Friedländer in 1882. 129-138. The chest films of 58 patients with proved pneumonia due to Pseudomonas, Klebsiella, Enterobacter, Escherichia coli, Proteus, or Bacteroides were reviewed.Pseudomonas pneumonia was characterized by diffuse alveolar involvement with rapid progression to extensive macrocavitation. Risk factors for Klebsiella pneumonia include alcoholism, diabetes mellitus, and COPD. Klebsiella pneumoniae is a Gram-negative bacillus with worldwide distribution that usually causes respiratory and urinary tract infections, ... Four weeks after admission, following discussion with Radiology, a thoracic CT scan was performed for subsequent biopsy of one of the pulmonary lesions. 2008;21 (2): 305-33, table of contents. Volume: 260 Issue: 1 pp. Unable to process the form. 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