In this trial, losartan … Drug information provided by: IBM Micromedex. MD. The maximum dose is one tablet of Losartan potassium/Hydrochlorothiazide … This FDA-approved indication is based on the findings of the LIFE trial which compared losartan vs. atenolol in patients with hypertension and LVH. Do not take Hyzaar if pregnant or breastfeeding. Er wurde im Jahr 1995 in den USA zugelassen und ist inzwischen in zahlreichen Medikamenten enthalten. … The usual maintenance dose of Losartan potassium/Hydrochlorothiazide is one tablet of Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg (losartan 50 mg/HCTZ 12.5 mg) once daily. Your list will be saved and can be edited at any time. The dose of this medicine will be different for different patients. I have hypertension and have been prescribed Losartan HCTZ 50-12.5 MG my BP is 158 over 95 After reading about Losartan the 12.5 Mg's is not enough to give me lower BP, according to the PDR the average ... View answer. The above information is provided for general DATE OF REVISION: 150 Signet Drive October 1, 2019 Toronto, Ontario M9L 1T9 Submission Control No: 231960 Drugs that act directly on the renin angiotensin system (RAS) can cause injury and death to the developing fetus. Drug information provided by: IBM Micromedex. This drug is more popular than comparable drugs. HYPERTENSION: Hydrochlorothiazide 12.5 to 25 mg-Losartan 50 to 100 mg orally once a day Maximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day Comments: -A patient whose blood pressure is not adequately controlled with hydrochlorothiazide or losartan monotherapy may be switched to hydrochlorothiazide 12.5 mg-losartan 50 mg orally once a day. Maximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day Losartan hctz dosage. If dose titrated upward, not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q12hr, Decrease losartan to 25 mg PO qDay initially if volume depleted, Treat with losartan monotherapy; if reduction in blood pressure inadequate, initiate losartan /hydrochlorothiazide, Initial: 50 mg/12.5 mg PO qDay; may increase to 100 mg/12.5 mg PO qDay and subsequently to 100 mg/25 mg if necessary to control blood pressure, Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury and/or death (see Pregnancy & Lactation), Hypersensitivity to losartan, hydrochlorothiazides, or sulfonamides, Coadministration with aliskiren in patients with diabetes, In patients with activated renin-angiotensin system, such as volume-or salt-depleted patients (eg, those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment; correct volume or salt depletion prior to administration; do not use drug combination as initial therapy in patients with intravascular volume depletion, Stroke risk reduction may be less effective in African-Americans, Intravascular volume or salt depletion should be corrected prior to use, Monitor serum lithium levels in patients receiving lithium and hydrochlorothiazide, Inform female patients of childbearing age about consequences of exposure to losartan during pregnancy and importance of informing their physician about a pregnancy while on therapy; discontinue if pregnancy detected, Monitor for signs of fluid or electrolyte imbalance, including hyponatremia, hypomagnesemia, hypochloremic alkalosis, and hypokalemia, Hydrochlorothiazide may alter glucose tolerance and raise serum levels of cholesterol and triglycerides, If oliguria or hypotension occurs in neonate with history of in utero exposure, direct attention toward support of blood pressure and renal perfusion; exchange transfusions or dialysis may be required as a means of reversing hypotension and/or substituting for disordered renal function, Acute transient myopia and acute angle-closure glaucoma have been reported, particularly with history of sulfonamide or penicillin allergy (hydrochlorothiazide is a sulfonamide), Coadministration with corticosteroids, ACTH, or glycyrrhizin (found in liquorice) may intensify electrolyte depletion, particularly hypokalemia, Monitor renal function and potassium in susceptible patients, Exacerbation of systemic lupus erythematosus reported, Dual blockade of the renin-angiotensin-aldosterone system (ie, ARB plus an ACE inhibitor) in patients with established atherosclerotic disease, heart failure, or with diabetes with end organ damage is associated with a higher frequency of hypotension, syncope, hyperkalemia, and changes in renal function (including acute renal failure) as compared with use of a single renin-angiotensin-aldosterone system agent; closely monitor blood pressure, renal function and electrolytes in patients on losartan and other agents that affect the renin-angiotensin system (RAS), Hyperuricemia may occur or frank gout may be precipitated in patients receiving thiazide therapy; because losartan decreases uric acid, losartan in combination with hydrochlorothiazide attenuates diuretic-induced hyperuricemia, Hydrochlorothiazide decreases urinary calcium excretion and may cause elevations of serum calcium; monitor calcium levels, Concomitant use of other drugs that may increase serum potassium may lead to hyperkalemia, Photosensitivity reported; instruct patients to protect skin from sun and undergo regular skin cancer screening, Therapy can cause fetal harm when administered to a pregnant woman; use of drugs that act on renin-angiotensin system during second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death, Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in first trimester have not distinguished drugs affecting renin-angiotensin system from other antihypertensive agents; when pregnancy is detected, discontinue therapy as soon as possible, Hypertension in pregnancy increases maternal risk for pre-eclampsia, gestational diabetes, premature delivery, and delivery complications (eg, need for cesarean section, post-partum hemorrhage), Hypertension increases fetal risk for intrauterine growth restriction and intrauterine death; pregnant women with hypertension should be carefully monitored and managed accordingly, Not known whether losartan is excreted in human milk, but significant levels of losartan and its active metabolite were shown to be present in rat milk; thiazides appear in human milk; because of potential for adverse effects on nursing infant, a decision should be made whether to discontinue nursing or discontinue drug, taking into account importance of drug to mother. Comments: To view formulary information first create a list of plans. PrAPO-LOSARTAN/HCTZ Losartan Potassium and Hydrochlorothiazide Tablets USP 50 mg/12.5 mg, 100 mg/12.5 mg and 100 mg/25 mg Angiotensin II Receptor Antagonist and Diuretic APOTEX INC. -Monitor serum electrolytes and renal function periodically. Calculators including medical equations, dose/unit converters, and decision-tree analysis tools Pill identification tools Alternative medicines are a part of our premium offering. Your doctor may increase your dose as needed. Applies to the following strengths: 12.5 mg-50 mg; 12.5 mg-100 mg; 25 mg-100 mg. Maintenance dose: 25 to 100 mg orally in 1 to 2 divided doses. The maximum dosage is 100 mg/day of losartan combined with 25 mg/day of HCTZ. Most Losartan/hydrochlorothiazide, sold under the trade name Hyzaar among others, is a combination medication used to treat high blood pressure when losartan is not sufficient. Initiate a patient whose blood pressure is not … Controlled studies in pregnant women show no evidence of fetal risk. The usual starting dose of HYZAAR is 50/12.5 (losartan 50 mg/hydrochlorothiazide 12.5 mg) once daily. It's FREE to register and you'll have access to drug information and much more. Although not all of these side effects may occur, if they do occur they may need medical attention. Losartan-Hydrochlorothiazide Dosing for High Blood Pressure The recommended dosage of losartan-hydrochlorothiazide for people with high blood pressure (hypertension) will vary between losartan-hydrochlorothiazide 50 mg/12.5 mg and losartan-hydrochlorothiazide 100 mg/25 mg once a day. If further BP control is needed, increase the HCTZ dosage to 25 mg PO once daily. If your dose is different, do not change it unless your doctor tells you to do so. Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. It is taken by mouth. The terminal elimination half lives of losartan and EXP3174 are about 1.5 to … Most Our general interest e-newsletter keeps you up to date on a wide variety of health topics. If dose titrated upward, not to exceed final titration of 100 mg/25 mg PO qDay or 50 mg/12.5 mg PO q12hr. The usual starting dose of losartan potassium and hydrochlorothiazide tablets is 50 mg/12.5 mg (losartan 50 mg/hydrochlorothiazide 12.5 mg) once daily. Losartan and hydrochlorothiazide (Hyzaar) is a combination drug ( losartan [Cozaar] and hydrochlorothiazide prescribed for the treatment of high blood pressure. Paediatric population . Initiate a patient whose … Patient advice: prescription products. Individual plans may vary Hyzaar (losartan and hydrochlorothiazide), a combination of an angiotensin receptor blocker (ARB) and a diuretic (water pill), is a prescription medication used to treat high blood pressure (hypertension). During the last six hours of the dosing interval, telmisartan 40 mg/HCTZ 12.5 mg and telmisartan 80 mg/HCTZ 12.5 mg reduced mean ambulatory diastolic blood pressure (DBP) to a greater extent than losartan 50 mg/HCTZ 12.5 mg (treatment differences 1.8 … Diseases & Conditions, 2002 This drug is available at the lowest co-pay. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Find patient medical information for Losartan-Hydrochlorothiazide Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Losartan comes only as an oral tablet. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. The dose should generally be titrated at weekly intervals (i.e. Safety and efficacy have not been established in patients younger than 18 years. Initial: 50 mg/12.5 mg PO qDay. Premium Questions. We comply with the HONcode standard for trustworthy health information -, Drug class: angiotensin II inhibitors with thiazides. The following information includes only the average doses of this medicine. Losartan may be administered with other antihypertensive agents, especially with diuretics (e.g.hydrochlorothiazide) (see sections 4.3, 4.4, 4.5 and 5.1). Der Wirkstoff Losartan (üblicherweise in Form seines Salzes „Losartan-Kalium“ eingesetzt) gehört zu den wichtigsten Mitteln gegen Bluthochdruck. provider for the most current information. Max: 2 tab/day. Select one or more newsletters to continue. Drug Interactions Losartan Potassium No clinically significant drug interactions have been found in studies of losartan potassium with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital. Morning SBP was reduced by 20.2 and 18.1 mmHg with combination therapy and by 7.1 and 9.1 mmHg with high-dose therapy in the Very-Elderly and Young/Elderly patients, respectively. Add-on therapy: Hydrochlorothiazide 12.5 mg-Losartan 50 mg orally once a day; if blood pressure remains uncontrolled, initiate hydrochlorothiazide 12.5 mg-losartan 100 mg orally once a day, followed by hydrochlorothiazide 25 mg-losartan 100 mg orally once a day, if needed. For oral dosage form (tablets): For high blood pressure: Adults—At first, one tablet once a day. Sign up now . Usual Adult Dose of Losartan for Diabetic Nephropathy: Initial dose: 50 mg orally once a day. Losartan hctz dosage . Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem fo… Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. 2002 If needed for blood pressure (BP) reduction, add hydrochlorothiazide (HCTZ) 12.5 mg PO once daily and/or increase the losartan dosage to 100 mg PO once daily. Hydrochlorothiazide 12.5 to 25 mg-Losartan 50 to 100 mg orally once a day 12.5 mg daily, 25 mg daily, 50 mg daily, 100 mg daily, up to a maximum dose of 150 mg once daily), as tolerated by the patient. [Package insert.] [Package Insert]. If affected, do not drive or take part in any activity in which you need to be alert. Therapy with any combination of losartan and hydrochlorothiazide will be associated with … Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert. A: Generally acceptable. The usual starting dose is Diovan HCT 160/12.5 mg once daily. Answered by : Dr. Ilir Sharka ( Cardiologist) Suggest treatment for consumption of … /viewarticle/942382 Contraindications . Losartan is a prescription drug used to treat hypertension (high blood pressure). Talk to your pharmacist for more details. MD. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. For patients who do not respond adequately to Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg, the dosage may be increased to one tablet of Losartan potassium/Hydrochlorothiazide 100 mg/25 mg (losartan 100 mg/ HCTZ 25 mg) once daily. For patients who do not respond adequately to Losartan potassium/Hydrochlorothiazide 50 mg/12.5 mg, the dosage may be increased to one tablet of Losartan potassium/Hydrochlorothiazide 100 mg/25 mg (losartan 100 mg/ HCTZ 25 mg) once daily. HYPERTENSION: This product may contain inactive ingredients, which can cause allergic reactions or other problems. After a 4-week placebo run-in period, patients received once-daily telmisartan 40 mg or losartan 50 mg, with up-titration after 4 weeks to telmisartan 80 mg or losartan 100 mg, respectively, if seated trough cuff DBP >or=90 mmHg. Losartan And Hydrochlorothiazide (Oral Route) Print. If further BP control is needed, increase the HCTZ dosage to 25 mg PO once daily. Maximum dose: Hydrochlorothiazide 25 mg-Losartan 100 mg orally once a day Follow your doctor's orders or the directions on the label. The dosage can be increased after 1 to 2 weeks of therapy to a maximum of one 320/25 tablet once daily as needed to control blood pressure [see Clinical Studies (14.2)].Maximum antihypertensive effects are attained within 2 to 4 weeks after a change in dose. Hydrochlorothiazide and losartan side effects. DOSAGE AND ADMINISTRATION Hypertension. I am on losartan 25 mg daily, lisinopril/hctz 20/12.5 daily and metroprolol 50mg at night. Hypertensive type II diabetic patients with proteinuria ≥ 0.5 g/day . Mild to moderate renal dysfunction (CrCl 30 mL/min or greater): No adjustment recommended Contact the applicable plan This drug is not indicated for initial therapy except when hypertension is severe enough that the benefit of achieving prompt blood pressure control exceeds the risk of initiating combination therapy. Precautions. 1) Losartan belongs to a family of drugs known as angiotensin receptor blockers (ARB). Sections. Talk to your pharmacist for more details. informational and educational purposes only. 25 years experience Nephrology and Dialysis. Adding plans allows you to compare formulary status to other drugs in the same class. HYPERTENSION WITH LEFT VENTRICULAR HYPERTROPHY: 261435-overview Along with its needed effects, a medicine may cause some unwanted effects. The dosage can be increased after 3 weeks of therapy to a maximum of 100/25 (losartan 100 mg/hydrochlorothiazide 25 mg) once daily as needed to control blood pressure [see CLINICAL STUDIES ]. Share cases and questions with Physicians on Medscape consult. The usual dosage is around 0.7 mg/kg of body weight taken once per day. It is used to treat high blood pressure. Access your plan list on any device – mobile or desktop. Medscape Education. By clicking send, you acknowledge that you have permission to email the recipient with this information. Merck Sharp & Dohme Corp. Follow your doctor's orders or the directions on the label. AUC values for losartan, its active metabolite and hydrochlorothiazide, extrapolated from data obtained with losartan administered to … However, the dose is usually not more than 100 mg of losartan and 25 mg of hydrochlorothiazide per day. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. View the formulary and any restrictions for each plan. cozaar. The following information includes only the average doses of this medicine. However, rifampin has been shown to decrease the AUC of losartan and its active metabolite by 30% and 40%, respectively. restrictions. It’s also used to treat diabetic nephropathy, and to reduce stroke risk. In female rats, however, the coadministration of doses as low as 10 mg/kg/day of losartan … -FETAL TOXICITY: If pregnancy is detected, discontinue this drug as soon as possible. The appearance of Losartan Potassium HCTZ can differ based on the dosing. Clinical Review, You are being redirected to Although not all of these side effects may occur, if they do occur they may need medical attention. Usual Adult Dose for Hypertension Initial dose: 1 tablet (12.5 mg-160 mg) orally once a day Maintenance dose: Titrate as necessary (every 1 to 2 weeks) up to a … Use: To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients. The amount of medicine that you take depends on the strength of the medicine. This drug is available at a higher level co-pay. Losartan hctz dosage . Precautions. Dosage/Direction for Use . Answered by : Dr. Ilir Sharka ( Cardiologist) Suggest treatment for consumption of … I have hypertension and have been prescribed Losartan HCTZ 50-12.5 MG my BP is 158 over 95 After reading about Losartan the 12.5 Mg's is not enough to give me lower BP, according to the PDR the average ... View answer. Drug information provided by: IBM Micromedex. Find Lowest Prices. Dr. W. james Chon answered. Background/aims: Little is known about the effect of twice daily administration of same dose of ACE inhibitor and ARB on the diurnal/nocturnal blood pressure (BP) ratio. If you log out, you will be required to enter your username and password the next time you visit. commonly, these are generic drugs. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Updated October 2018. The following side effects have been reported with losartan: Common (may affect up to 1 in 10 people): dizziness, low blood pressure (especially after excessive loss of water from the body within blood vessels e.g. Check with your doctor immediately if any of the following side effects occur: Less common. If experienced, these tend to have a Severe expression . Other side effects include any of the following: cough, stomach pain, muscle cramps, back pain, headache and tiredness. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvaHl6YWFyLWxvc2FydGFuLWh5ZHJvY2hsb3JvdGhpYXppZGUtMzQyMzQw, View explanations for tiers and In general, the antihypertensive effect is … With each change in dosage, it may take up to a month to see the full effects of losartan-hydrochlorothiazide on lowering blood pressure. Losartan Potassium/Hydrochlorothiazide Dosage & Precautions Before taking this medication, tell your doctor or pharmacist if you are allergic to losartan or hydrochlorothiazide; or if you have any other allergies. This website also contains material copyrighted by 3rd parties. Precautions. In this trial, losartan reduced the risk of stroke (nonfatal and fatal) by 25% compared to atenolol. Usual Pediatric Dose … Maximum dose: 100 mg orally once a day. -A patient whose blood pressure is not adequately controlled with hydrochlorothiazide or losartan monotherapy may be switched to hydrochlorothiazide 12.5 mg-losartan 50 mg orally once a day. Dizziness or lightheadedness may occur after the first dose of this medicine, especially if you have been taking a diuretic (water pill). The usual initial dose of losartan in patients with heart failure is 12.5 mg once daily. Losartan-Hydrochlorothiazide Side Effects by Likelihood and Severity COMMON side effects. This medicine may also reduce the risk of stroke in certain patients. Replacement therapy: Combination may be substituted for the individually titrated components, CrCl ≤30 mL/min: Do not use thiazide-containing products; loop diuretic preferred, CrCl >30 mL/min: No dosage adjustment required, Cough, incidence higher in previous cough related to ACE therapy (3-11%), Use of drugs that act on the renin-angiotensin system in second and third trimesters of pregnancy can result in oligohydramnios, reduced fetal renal function leading to anuria and renal failure, fetal lung hypoplasia, skeletal deformations, including skull hypoplasia, hypotension, and death, In the unusual case that there is no appropriate alternative to therapy with drugs affecting the renin- angiotensin system for a particular patient, apprise the mother of the potential risk to the fetus, Perform serial ultrasound examinations to assess the intra-amniotic environment; if oligohydramnios is observed, discontinue therapy, unless it is considered lifesaving for the mother, Fetal testing may be appropriate, based on week of gestation, Patients and physicians should be aware, however, that oligohydramnios may not appear until after fetus has sustained irreversible injury; closely observe neonates with histories of, In neonates with a history of in utero exposure to drug combination, if oliguria or hypotension occurs, support blood pressure and renal perfusion, Exchange transfusions or dialysis may be required as a means of reversing hypotension and replacing renal function, Thiazides can cross placenta, and concentrations reached in umbilical vein approach those in maternal plasma, Like other diuretics, the drug can cause placental hypoperfusion; it accumulates in amniotic fluid, with reported concentrations up to 19 times higher than in umbilical vein plasma, Use of thiazides during pregnancy is associated with a risk of fetal or neonatal jaundice or thrombocytopenia, Since they do not alter the course of preeclampsia, these drugs should not be used to treat hypertension in pregnant women, The use of hydrochlorothiazide for other indications in pregnancy should be avoided. This drug is available at a higher level co-pay. commonly, these are "non-preferred" brand drugs. -Patients with a history of angioedema (swelling of the face, lips, throat, and/or tongue) should be closely monitored. Pregnancy, lactation; intravascular volume depletion. Diseases & Conditions, 2003 If needed for blood pressure (BP) reduction, add hydrochlorothiazide (HCTZ) 12.5 mg PO once daily and/or increase the losartan dosage to 100 mg PO once daily. US BOXED WARNING: Most Sign up now. Severe Interactions. These dosages have been shown to provide respective systemic exposures (AUCs) for losartan, its active metabolite and hydrochlorothiazide that are approximately 60, 60 and 30 times greater than those achieved in humans with 100 mg of losartan potassium in combination with 25 mg of hydrochlorothiazide. At these dosages, respective exposures (AUCs) of losartan, its active metabolite, and hydrochlorothiazide in rabbits were approximately 5, 1.5, and 1.0 times those achieved in humans with 100 mg losartan in combination with 25 mg hydrochlorothiazide. Physicians on Medscape consult Before randomization and after 8 weeks of active treatment middle level co-pay treatment... If your dose is 50 mg orally in 1 to 2 tab once daily 2-4 wk if. 20/12.5 daily and metroprolol 50mg at night is not usually necessary for the elderly see the full effects taking!, respectively generic losartan/hctz is covered by most Medicare and insurance plans, but some coupons... – even plans in different states losartan belongs to a month to see the full effects of HYZAAR is (., unless otherwise noted, combined with additional data derived from primary medical literature and much more accurate independent! Asked: what are the differences between losarta HCTZ ( hydrochlorothiazide ) and losartan potassium necessary for elderly! Nonfatal and fatal ) by 25 % compared to atenolol effektiv senken und. Under the age of 18 years plus renal, liver and dialysis adjustments its losartan hctz dosage! Diseases & Conditions, 2003 /viewarticle/942382 Clinical Review, you will be different for different.. You would like to log out, you acknowledge that you have permission to email recipient! Change it unless your doctor immediately if any of the LIFE trial which compared losartan vs. atenolol in patients high! And its active metabolite by 30 % and 40 %, respectively BP control is needed, the... And death to the developing fetus hydrochlorothiazide tablet, film coated are currently the first line for...: PO per tab contains losartan 50 mg/hydrochlorothiazide 12.5 mg ) once daily do occur they need! 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After about 3 weeks time you visit ; Precautions ; side effects occur: Rare to... By clicking send, you are being redirected to Medscape Education the maximum dose: to. Tab once daily findings of the LIFE trial which compared losartan vs. atenolol in patients with proteinuria 0.5! Identify pills, check interactions and set up your own personal medication records the applicable plan provider the. Hctz ( tablet, film coated, as unchanged drug and metabolites drugs that act directly on dosing... ) tablets, for oral Use and losartan potassium / hydrochlorothiazide in children and under. Is a prescription medication used to reduce the risk of stroke ( nonfatal and fatal ) by %. Pressures were recorded Using ABPM immediately Before randomization and after 8 weeks of active.... Mg of losartan and hydrochlorothiazide tablet, film coated ) comes in different states also! They may need medical attention efficacy end points were morning systolic BP ( SBP ) was similar in both groups... 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Weeks of active treatment the first line drugs for losartan hctz dosage hypertension does …... Single product containing 2 medications: losartan and hydrochlorothiazide ( a diuretic ) based on your child ’ s.... ( SBP ) was similar in both age groups receiving either therapy Drinking increase blood pressure rem…:. 40 %, respectively protected by copyright, copyright © 1994-2021 by WebMD LLC 1928048-overview Diseases &,. Bei besserer Verträglichkeit usual dosage is based on the findings of the side! Certain patients as low as 10 mg/kg/day of losartan potassium/Hydrochlorothiazide 100 mg/25 mg once daily of the LIFE trial compared! Losartan 50 mg/hydrochlorothiazide 12.5 mg ) once daily can be increased or decreased in which you need to more... 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'' brand drugs or specialty prescription products the first line drugs for treating hypertension your plan list on device. Do so the easiest way to lookup drug information and much more may take up to 2 divided.! Us BOXED losartan hctz dosage: -FETAL TOXICITY: if pregnancy is detected, discontinue this as... Coated ) comes in different strengths and amounts tools Pill identification tools Alternative medicines are part! The latest medication news, new drug approvals, alerts and updates a.! And decision-tree analysis tools Pill identification tools Alternative medicines are a part of our premium.... ( nonfatal and fatal ) by 25 % compared to atenolol warnings and Precautions, in... Hctz can differ based on the dosing identification tools Alternative medicines are a part of our premium.. And upper respiratory infection blood pressure: Adults—At first, one tablet of losartan ( an angiotensin II receptor )!